Different Characteristics of Cognitive Impairment in Elderly Schizophrenia and Alzheimers Disease in the Mild Cognitive Impairment Stage

We compared indices of the revised version of the Wechsler Memory Scale (WMS-R) and scaled scores of the five subtests of the revised version of the Wechsler Adult Intelligence Scale (WAISR) in 30 elderly schizophrenia (ES) patients and 25 Alzheimer’s disease (AD) patients in the amnestic mild cognitive impairment (aMCI) stage (AD-aMCI). In the WMS-R, attention/concentration was rated lower and delayed recall was rated higher in ES than in AD-aMCI, although general memory was comparable in the two groups. In WAIS-R, digit symbol substitution, similarity, picture completion, and block design scores were significantly lower in ES than in ADaMCI, but the information scores were comparable between the two groups. Delayed recall and Published online: January 6, 2011 E X T R A Hiroaki Kazui, MD, PhD This is an Open Access article licensed under the terms of the Creative Commons AttributionNonCommercial-NoDerivs 3.0 License (www.karger.com/OA-license), applicable to the online version of the article only. Distribution for non-commercial purposes only. Psychiatry, Department of Integrated Medicine, Division of Internal Medicine Osaka University Graduate School of Medicine, D3 2-2 Yamadaoka, Suita-City Osaka 565-0871 (Japan) Tel. +81 66 879 3051, Fax +81 66 879 3059, E-Mail kazui @ psy.med.osaka-u.ac.jp www.karger.com/dee DOI: 10.1159/000323561 D ow nl oa de d by : 54 .7 0. 40 .1 1 11 /1 8/ 20 17 7 :0 8: 40 P M 21 Dement Geriatr Cogn Disord Extra 2011;1:20–30 DOI: 10.1159/000323561 E X T R A Kazui et al.: Cognition in Elderly Schizophrenia and AD-aMCI www.karger.com/dee © 2011 S. Karger AG, Basel Published online: January 6, 2011 forgetfulness were less impaired, and attention, working memory and executive function were more impaired in ES than in AD-aMCI. These results should help clinicians to distinguish ES combined with AD-aMCI from ES alone. Copyright © 2011 S. Karger AG, Basel